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The Relationship Between Cutaneous Cellular Immune Responsiveness and Mortality in a Nursing Home Population
Author(s) -
COHN JOHN R.,
HOHL CAROLE A.,
BUCKLEY C. EDWARD
Publication year - 1983
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1983.tb03404.x
Subject(s) - medicine , nursing homes , immunity , population , cellular immunity , significant difference , antigen , immunology , immune system , nursing , environmental health
The survival over 18 months of 29 nursing home residents was compared with results of cutaneous testing of cell‐mediated immunity at the start of the period of observation. Eight antigens were used to evaluate immunity by intradermal injection of each antigen and measurement of the areas of induration at 48 and 72 hours. A difference in responses was seen between the survivors and those who died, although this difference was statistically significant at 72 hours only. As expected, survivors had more (3.1, compared with 1.47) and larger (8.6 mm, compared with 3.2 mm) reactions at 72 hours than those who died.