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Aspirin Absorption from a Feeding Jejunostomy
Author(s) -
Nelson Edward B.,
Levitt Jacqueline R.
Publication year - 1980
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1980.tb00008.x
Subject(s) - medicine , aspirin , dysphagia , absorption (acoustics) , population , gastroenterology , jejunostomy , surgery , parenteral nutrition , physics , environmental health , acoustics
In a 67‐year‐old man who had a feeding jejunostomy because of dysphagia paralytica, the absorption of aspirin was measured in terms of serum salicylate concentration. A 975‐mg dose of aspirin was given as a slurry in water directly into the feeding tube. Peak serum levels of salicylate were well correlated with those in previous studies of aspirin absorption by the oral route in a geriatric population. However, unexpectedly, the half‐life of the drug in this patient was twice as long (7.5 hours) as that found in six previous studies (3.7 hours) of elderly patients given similar doses.