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Procainamide‐Induced Systemic Lupus Erythematosus with Hypocomplementemia
Author(s) -
Rao K. V. R. Mohan,
Diaz Roberto,
Quigley Thomas J.
Publication year - 1977
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1977.tb00304.x
Subject(s) - procainamide , medicine , pharmacotherapy , complement (music) , lupus erythematosus , drug , systemic lupus erythematosus , dermatology , gastroenterology , immunology , pharmacology , antibody , disease , biochemistry , chemistry , complementation , gene , phenotype
Procainamide‐induced systemic lupus erythematosus (SLE) is a well recognized clinical syndrome believed to be characterized by normocomplementemia. However, in 7 cases of drug‐induced SLE recorded in the literature, hypocomplementemia was found. The present report concerns a well documented case of procainamide‐induced SLE with hypocomplementemia. The patient improved and complement values returned to normal after procainamide therapy was discontinued and replaced by digitalis and steroid therapy.