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Piperacetazine Versus Thioridazine in the Treatment of Organic Brain Disease: A Controlled Double‐Blind Study
Author(s) -
GOLDSTEIN S. E.,
BIRNBOM F.
Publication year - 1976
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1976.tb03311.x
Subject(s) - thioridazine , medicine , double blind , disease , brain disease , alternative medicine , placebo , pathology , chlorpromazine
in a double‐blind cross‐over study, 50 geriatric patients with organic brain disease were divided into two groups. One group first received piperacetazine for 15 days and then thioridazine for 15 days. For the other group the sequence was reversed. Piperacetazine proved to be at least as effective as thioridazine and seemed to be more effective against certain target symptoms; side effects were less common and less severe.