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Change in Antikaliuretic Response to Potassium‐Sparing Diuretics in Patients with Cirrhotic Ascites
Author(s) -
RADÓ JÁNOS P.
Publication year - 1976
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1976.tb03309.x
Subject(s) - medicine , ascites , potassium , cirrhosis , diuretic , gastroenterology , excretion , organic chemistry , chemistry
In 2 elderly patients with ascites due to hepatic cirrhosis, potassium excretion decreased during re‐administration of potassium‐sparing diuretics after recurrence of ascites following withdrawal of previous prolonged treatment. An exaggerated antikaliuretic response and a paradoxic rise in potassium excretion are “unpredictable” changes which may occur during administration of potassium‐sparing diuretics at different times in the same patient treated with the same drug.