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Thyroid‐Adrenocortical Relationships in the Safe Treatment of Arthritis, Allergy, and Skin Disorders with Prednisone
Author(s) -
Barnes Broda O.
Publication year - 1975
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1975.tb00631.x
Subject(s) - medicine , prednisone , cortisone , thyroid , hormone , rheumatoid arthritis , allergy , arthritis , endocrinology , dermatology , immunology
Although the anti‐inflammatory action of cortisone or its derivatives is efficacious in arthritis or certain allergic and skin diseases, the standard use of such compounds is limited to short‐term administration because of induced disturbances in mineral and glucose metabolism. Another side effect of cortisone is suppression of thyroid hormone secretion. The author has found that when thyroid therapy is prescribed for patients with arthritis (300 to date), certain skin diseases or selected allergic disorders, the addition of prednisone in a small dosage of 5–10 mg daily will produce further improvement for at least a five‐year period, without side effects. The thyroid and adrenocortical hormones apparently are synergistic in the treatment of arthritis and allergy.