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Predictive Medicine. XIII. Tolerance Testing
Author(s) -
CHERASKIN E.,
RINGSDORF W. M.
Publication year - 1972
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1972.tb00780.x
Subject(s) - medicine , impaired glucose tolerance , stimulus (psychology) , glucose tolerance test , diabetes mellitus , predictive testing , stress testing (software) , endocrinology , genetic testing , insulin resistance , psychology , computer science , programming language , psychotherapist
The prime purpose of tolerance testing is to elicit an exaggerated response to a particular stimulus, as when glucose loading is used to determine the glucose tolerance pattern. Examples are presented to show the relationship of age to alveolar bone loss in terms of glucose tolerance tests (glucose stress), and of age to blood glucose concentration (no glucose stress). The amplitudes of fluctuation in clinical and biochemical signs are compared in healthy versus sick subjects. In a predictive medicine system, the aim is to ascertain a predisposition to, or early evidence of pathosis. Therefore, data obtained under ordinary circumstances (no stress) serve adequately if it is recognized that physiologic values and normal values are not synonymous and that subtle changes may be predictive.