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Comparative Study of Coagulation, Fibrinolysis and Cardiorespiratory Function in Elderly and Young Subjects after Exercise *
Author(s) -
GIBELLI A.,
MORPURGO M.,
GIAROLA P.,
BEULCKE G.,
CASACCIA M.,
PETRINI C.,
RAMPULLA C.
Publication year - 1972
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1972.tb00771.x
Subject(s) - medicine , cardiorespiratory fitness , fibrinolysis , heart rate , blood pressure , coagulation , ventilation (architecture) , respiratory minute volume , cardiology , pulse rate , respiratory rate , respiratory system , physical therapy , anesthesia , mechanical engineering , engineering
Nine aged subjects (67 to 87 years old) and 9 young and adult persons were submitted to an exercise load (cycloergometer) varying between 1.0 to 1.5 W/kg. Tests of cardiorespiratory function, blood coagulation and fibrinolysis were carried out before and after exercise, and then after 5, 15 and 60 minutes. The increase of respiratory rate was more marked in the elderly subjects than in the young and adult persons. No differences were observed with respect to the increase of heart rate and blood pressure. The increase of oxygen “pulse” was considerably less pronounced in the elderly. The pulmonary ventilation and the ventilatory oxygen equivalent were significantly different after six minutes of exercise. No significant differences were observed for blood lactic and pyruvic acid, or for the blood coagulation indexes, including factor VIII. The increase in fibrinolytic activity was marked and constant, irrespective of age.