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AN ERGOT PREPARATION (HYDERGINE) IN THE TREATMENT OF CEREBROVASCULAR DISORDERS IN THE GERIATRIC PATIENT: DOUBLE‐BLIND STUDY
Author(s) -
Ditch Morris,
Kelly Francis J.,
Resnick Oscar
Publication year - 1971
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1971.tb02623.x
Subject(s) - medicine , placebo , double blind , anesthesia , physical therapy , alternative medicine , pathology
A bstract In a controlled double blind study, 40 geriatric patients with cerebrovascular disorders were treated with sublingual tablets of Hydergine or placebo for twelve weeks. The inventory of symptoms (32 items) included an array which portrayed their physical status, behavioral traits, and intellectual impairments. Final appraisals based on re‐evaluations at three‐week intervals during treatment showed that, compared to the placebo, Hydergine produced greater improvements in 19 of the 30 items rated. The most impressive results ascribable to Hydergine pertained to cognition and intellectual function. No untoward effects from this drug were observed during the course of this study. A probable mode of action of this ergot preparation is also discussed.