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AGING IN HIROSHIMA AND NAGASAKI ATOMIC BOMB SURVIVORS: ACCUMULATION OF CARDIAC LIPOFUSCIN
Author(s) -
Anderson Robert E.,
Yamamoto Tsutomu,
Oshida Kenzo,
Thorslund Todd
Publication year - 1971
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1971.tb02621.x
Subject(s) - lipofuscin , medicine , autopsy , ventricle , physiology , significant difference , cardiology , pathology
A bstract This report concerns the amount of age‐dependent lipofuscin in the myocardium (left ventricle) as found at autopsy in a group of 54 persons who had been exposed proximally (1,400 meters from the hypocenter) to the Hiroshima and Nagasaki atomic bombs of 1945. The subjects were matched by sex and age‐decade of death with a similar number of subjects who were in neither city at the time of the explosions. The results failed to demonstrate an accelerated accumulation of pigment in the proximally exposed group. Although the difference was not statistically significant, the majority of the exposed group appeared to accumulate lipofuscin more slowly than did the nonexposed group. The possible implications are discussed.