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NITROGENOUS COMPOUNDS IMMOBILIZED IN AN AGED RAT
Author(s) -
BJORKSTEN JOHAN,
ASHMAN STEPHEN
Publication year - 1970
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1970.tb02109.x
Subject(s) - medicine , litter , aspartic acid , lysine , tritium , arginine , serine , amino acid , tyrosine , residue (chemistry) , glutamic acid , zoology , biochemistry , biology , enzyme , ecology , physics , nuclear physics
A bstract : A pregnant rat received 8 mc of tritiated tyrosine at the time of giving birth (from seven days before, to six days after). No radioisotopes were ever given directly to the litter born. A male from this litter died from pneumonia at age 809 days. After removal of water and acetone solubles and of phospholipids, hydrolysis of the residue released the following radioactive amino acids, parts of molecules fixed until death and containing tritium present at birth: lysine, arginine, aspartic acid, glutamic acid, serine, listed in order of decreasing radioactivity, with lysine carrying 29 per cent of the total tritium present.