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VARIABLES IN HOST RESISTANCE PERTAINING TO SEPTICEMIA. I. BLOOD GLUCOSE LEVEL
Author(s) -
Robson Martin C.,
Heggers John P.
Publication year - 1969
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1969.tb02339.x
Subject(s) - medicine , diabetes mellitus , host factors , host (biology) , sepsis , gram , microbiology and biotechnology , intensive care medicine , bacteria , immunology , endocrinology , biology , ecology , virus , genetics
A bstract Many factors are important in host resistance to infection, but the mechanisms have not been elucidated. This study of 267 cases of septicemia concerns one factor of host resistance—the blood glucose level. It appears to affect Gram‐negative organisms differently from Gram‐positive organisms. The average concentration of blood glucose in the patients with Gram‐negative septicemia was significantly lower than in the patients with Gram‐positive septicemia, regardless of the presence or absence of diabetes mellitus. It is suggested that this relationship, as gleaned from our retrospective clinical study, be investigated further as a possible means of elucidating and monitoring over‐all host resistance to infection.
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