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SYNOVIAL FLUID: DIAGNOSTIC FEATURES AND METHODS FOR EXAMINATION
Author(s) -
SCHMID FRANK R.
Publication year - 1968
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1968.tb02094.x
Subject(s) - synovial fluid , medicine , gout , pathology , synovial membrane , rheumatoid arthritis , fibrin , inflammation , osteoarthritis , immunology , alternative medicine
A bstract : The functions of synovial membrane and synovial fluid are described, as well as the changes that occur during inflammation, particularly in gout and rheumatoid arthritis. Methods for examination of the synovial fluid are given in detail, involving the gross appearance of the fluid, the collection of the specimen, the cytology, fibrin clot formation, mucin clot formation, viscosity, detection of crystals, and simultaneous determination of blood and synovial fluid glucose. Interpretations are discussed. A fairly complete examination of synovial fluid is possible with a minimum of equipment and within a reasonable time. The significance of the findings outweighs the effort of the analysis. Proper interpretation of synovianalysis will greatly aid in diagnosis, offer some insight concerning prognosis, provide a measure of the therapeutic response and add to understanding of the pathogenesis of synovial‐tissue inflammation.