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A BISACODYL SUPPOSITORY AS AN ENEMA SUBSTITUTE
Author(s) -
PHILLIPS ROSWELL W.
Publication year - 1965
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1965.tb00576.x
Subject(s) - bisacodyl , suppository , medicine , laxative , enema , gastroenterology , cathartic , rectum , constipation , pharmacology , colonoscopy , colorectal cancer , cancer
Despite the availability of numerous effective laxatives, a certain number of patients still require enemas for satisfactory evacuation of the contents of the lower gastrointestinal tract. Many are debilitated and chronically ill. This report describes our experience with a local‐contact type of suppository as an enema substitute in such patients. Bisacodyl, or bis (p‐acetoxyphenyl)‐2‐pyridylmethane 1 , is said to exert its laxative effect in the colon through reflex action upon contact with the mucosal nervous plexi (1). Its action is said to be independent of intestinal tone (2) and can be abolished by anesthetizing the rectosigmoid mucosa (3). The suppository contains 10 mg of the drug.