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MULTIDISCIPLINARY PAIN ABSTRACTS: 45
. Pain (45)
Publication year - 2004
Publication title -
pain practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 58
eISSN - 1533-2500
pISSN - 1530-7085
DOI - 10.1111/j.1530-7085.2004.4007_45.x
Subject(s) - medicine , nociceptor , osteoarthritis , percutaneous vertebroplasty , dentistry , temporomandibular joint , soft tissue , subchondral bone , joint pain , pain relief , nociception , surgery , articular cartilage , pathology , vertebral body , alternative medicine , receptor
Pain in degenerative bone and joint disease is usually attributed to sensitized nociceptors in inflamed periarticular soft tissues. In this article, the authors draw attention to the potential contribution of intrinsic bone innervation. Although some dental pain derives from inflamed periodontal soft tissue, a more important source is the dentine and root canal. By analogy, pain on weight bearing in osteoarthritis and related conditions may be due to compressive forces applied to the innervation of subchondral bone exposed by erosion of the overlying cartilage. Pain relief obtained by injecting acrylic cement into the bone interior during percutaneous vertebroplasty is consistent with this concept. The development of a new family of pain relief options based on “marrow canal treatment” may be a realistic possibility.