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Ethanol, Glutamate, and the Ventral Tegmental Area—A Commentary on: Ding, Engleman, Rodd, and McBride, “Ethanol Increases Glutamate Neurotransmission in the Posterior Ventral Tegmental Area of Female Wistar Rats”
Author(s) -
Olive M. Foster
Publication year - 2012
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.2012.01816.x
Subject(s) - ventral tegmental area , microdialysis , glutamate receptor , glutamatergic , neuroscience , dopaminergic , dopamine , chemistry , medicine , biology , receptor
The recent study by Ding and colleagues (2012) utilized in vivo microdialysis to demonstrate that acute and repeated alcohol administration produces dose‐dependent effects on extracellular levels of the glutamate in the posterior ventral tegmental area. These findings have important implications for interactions between glutamatergic and dopaminergic mediation of alcohol reinforcement in the ventral midbrain.