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Management of Alcoholic Liver Disease: An Update
Author(s) -
Kershenobich David,
Corona Dana Lau,
Kershenovich Ruben,
GutierrezReyes Gabriela
Publication year - 2011
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.2010.01402.x
Subject(s) - alcoholic liver disease , medicine , disease , liver disease , inflammation , abstinence , fatty liver , alcoholic hepatitis , fibrosis , bioinformatics , biology , cirrhosis , psychiatry
Treatment of alcoholic liver disease is for the most part based on the stage of the disease and the pathogenic event that is being targeted. The primary treatment modalities that are considered in the treatment of alcoholic liver disease include abstinence, agents that suppress inflammation, anticytokine therapy, nutritional support, modifiers of alcohol metabolism, anti‐oxidants, and inhibitors of hepatic fibrosis. Future therapeutic options include exploration of new pathways such as the patatin‐like phospholipase domain containing 3 protein (PNPLA‐3).