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Potential Neuroprotective Effects of Acamprosate
Author(s) -
Koob George F.,
Mason Barbara J.,
Witte Philippe,
Littleton John,
Siggins George R.
Publication year - 2002
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.2002.tb02578.x
Subject(s) - acamprosate , neuroprotection , nmda receptor , neurotoxicity , glutamate receptor , neuroscience , pharmacology , psychology , medicine , antagonist , receptor , toxicity , naltrexone
This article represents the proceedings of a symposium at the 2001 RSA Meeting in Montreal, Canada. The organizers were Barbara J. Mason and George F. Koob. Anita M. Goodman served as chair. The presentations were (1) Acamprosate inhibits alcohol withdrawal‐induced neurotoxicity in organotypic hippocampal cultures, by John Littleton; (2) Acamprosate alteration of NMDA receptor‐dependent synaptic transmission and synaptic plasticity, by George R. Siggins; (3) Acamprosate and glutamate during ethanol withdrawal, by Philippe De Witte; (4) Clinical evidence of protective CNS effects of acamprosate in alcohol‐dependent individuals, by Barbara J. Mason.