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Pharmacological Relapse Prevention in Alcohol Dependence: From Animal Models to Clinical Trials
Author(s) -
Boening Jobst AugustLudwig,
Lesch Otto Michel,
Spanagel Rainer,
Wolffgramm Jochen,
Narita Minoru,
Sinclair David,
Mason Barbara J.,
Wiesbeck Gerhard A.
Publication year - 2001
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.2001.tb02386.x
Subject(s) - naltrexone , alcohol addiction , acamprosate , relapse prevention , serotonergic , addiction , dopaminergic , alcohol dependence , craving , animal model , pharmacology , psychology , medicine , psychiatry , neuroscience , psychotherapist , alcohol , receptor , antagonist , serotonin , dopamine , biology , biochemistry
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Jobst August‐Ludwig Boening and Otto Michel Lesch. The presentations were (1) Pharmacological validation of a new animal model of alcoholism, by Rainer Spanagel; (2) Persisting loss of control as main criterion for alcohol addiction in rats and mice, by Jochen Wolffgramm; (3) Role of NMDA receptor subunits associated with protein kinase C in the prevention of alcohol dependence, by Minoru Narita; (4) Long‐term follow up of continued naltrexone treatment, by David Sinclair; (5) Pharmacological treatment trials with dopaminergic and serotonergic substances: Myths or facts? by Gerhard A. Wiesbeck; and (6) Methodology and behavioral therapy of the U.S. acamprosate study, by Barbara J. Mason.