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Alcohol Actions on GABA A Receptors: From Protein Structure to Mouse Behavior
Author(s) -
Ueno Susumu,
Harris R. Adron,
Messing Robert O.,
SanchezPerez A. M.,
Hodge C. W.,
McMahon T.,
Wang D.,
Mehmert K. K.,
Kelley S. P.,
Haywood A.,
Olive M. F.,
Buck Kari J.,
Hood Heather M.,
Blednov Yuri,
Findlay Geoffrey,
Paola Mascia Maria
Publication year - 2001
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.2001.tb02378.x
Subject(s) - allosteric regulation , receptor , protein subunit , mutagenesis , gabaa receptor , glycine , amino acid , chemistry , biology , neuroscience , biochemistry , gene , mutation
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were R. Adron Harris and Susumu Ueno. The presentations were (1) Protein kinase Cɛ‐regulated sensitivity of γ‐aminobutyric acid type A (GABA A ) receptors to allosteric agonists, by Robert O. Messing, A. M. Sanchez‐Perez, C. W. Hodge, T. McMahon, D. Wang, K. K. Mehmert, S. P. Kelley, A. Haywood, and M. F. Olive; (2) Genetic and functional analysis of a GABA A receptor γ2 subunit variant: A candidate for quantitative trait loci involved in alcohol sensitivity and withdrawal, by Kari J. Buck and Heather M. Hood; (3) Tryptophan‐scanning mutagenesis in GABA A receptor subunits: Channel gating and alcohol actions, by Susumu Ueno; and (4) Can a single binding site account for actions of alcohols on GABA A and glycine receptors? by R. Adron Harris, Yuri Blednov, Geoffrey Findlay, and Maria Paola Mascia.