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Transgenic and Gene “Knockout” Models in Alcohol Research
Author(s) -
Hoffman Paula L.,
Yagi Takeshi,
Tabakoff Boris,
Phillips Tamara J.,
Kono Hiroshi,
Messing Robert O.,
Choi DooSup
Publication year - 2001
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.2001.tb02375.x
Subject(s) - gene knockout , knockout mouse , transgene , fyn , genetically modified mouse , microbiology and biotechnology , biology , signal transduction , neuroscience , tyrosine kinase , receptor , gene , genetics
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Paula L. Hoffman and Takeshi Yagi. The presentations were (1) cAMP signaling in ethanol sensitivity and tolerance, by Boris Tabakoff; (2) Synaptic signaling pathways of Fyn‐tyrosine kinase, by Takeshi Yagi; (3) Ethanol drinking and sensitization in dopaminergic and serotonergic receptor knockouts, by Tamara J. Phillips; (4) ICAM‐1 is involved in early alcohol‐induced liver injury in the mouse given enteral alcohol, by Hiroshi Kono; and (5) Strategies for targeted and regulated knockouts, by Robert O. Messing and Doo‐Sup Choi.