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Premorbid Risk Factors for Alcohol Dependence in Antisocial Personality Disorder
Author(s) -
Yoshino Aihide,
Fukuhara Taihei,
Kato Motoichiro
Publication year - 2000
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.2000.tb04550.x
Subject(s) - alcohol dependence , family history , antisocial personality disorder , conduct disorder , alcohol use disorder , psychology , psychiatry , alcohol , personality , risk factor , clinical psychology , medicine , poison control , injury prevention , chemistry , medical emergency , social psychology , biochemistry
Background: Many, but not all, types of antisocial personality disorders (ASP) are complicated by alcohol dependence. Therefore, some additional risk factors may exist for alcohol dependence co‐occurring with ASP. We studied whether severe childhood conduct disorder and a family history of alcohol dependence are possible risk factors for the development of alcohol dependence in ASP. Methods: The subjects were 81 male Japanese criminals diagnosed with DSM‐III‐R ASP. Relative risks of alcohol dependence for severe conduct disorder and for a positive family history were estimated by using a multiple logistic model. Results: Forty‐three subjects (53.0%) met criteria for DSM‐111‐R alcohol dependence. The relative risk of alcohol dependence for severe conduct disorder ( n = 44), compared with mild conduct disorder, was 4.1; whereas the relative risk for a positive family history ( n = 31), relative to a negative family history, was 1.9. Severe childhood conduct disorder was also associated with severe adulthood antisocial behavior and an earlier onset of alcohol dependence. Conclusions: The results suggest that severe childhood conduct disorder and a positive family history of alcohol dependence are independent premorbid risk factors for developing alcohol dependence among persons with ASP.