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γ‐Glutamyltranspeptidase and Carbohydrate Deficient Transferrin: Alternative Measures of Excessive Alcohol Consumption
Author(s) -
Litten Raye Z.,
Allen John P.,
Fertig Joanne B.
Publication year - 1995
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1995.tb01021.x
Subject(s) - carbohydrate deficient transferrin , transferrin , alcohol consumption , carbohydrate , consumption (sociology) , alcohol , medicine , biology , biochemistry , social science , sociology
Both γ‐glutamyltranspeptidase and carbohydrate‐deficient transferrin have been extensively researched as biological markers of heavy alcohol consumption. The current study briefly describes each test, identifies subject variables that influence their relative sensitivities and specificities, and examines issues surrounding use of the two markers in combination. In addition, this study suggests five design features that should characterize projects evaluating the validity of biochemical markers.