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Frontal P300 Decrements in Antisocial Personality Disorder
Author(s) -
Bauer Lance O.,
O'Connor Sean,
Hesselbrock Victor M.
Publication year - 1994
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1994.tb01427.x
Subject(s) - psychology , borderline personality disorder , audiology , oddball paradigm , antisocial personality disorder , personality , event related potential , developmental psychology , continuous performance task , electroencephalography , clinical psychology , poison control , cognition , psychiatry , injury prevention , medicine , social psychology , environmental health
Event‐related potentials (ERPs) were recorded from 83, 21‐ to 25‐year‐old nonalcoholic men varying in alcoholism vulnerability due to the presence/absence of an alcoholic family history or a personal history of antisocial personality disorder. ERPs were elicited by a visual oddball task in which the target was presented more frequently than the nontarget, in order to elicit impulsive or perseverative responding. Analyses of N200 and P300 revealed no group differences in the nontarget response. However, analyses of the target response revealed a significantly smaller P300 in the antisocial personality (ASP)+ group compared with the ASP‐ group. The P300 decrement was limited to frontal electrode sites and is interpreted as indicating the presence of subtle anterior brain dysfunction among ASP+ subjects.
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