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Ethanol Patch Test—A Simple and Sensitive Method for Identifying ALDH Phenotype
Author(s) -
Murarnatsu Taro,
Higuchi Susumu,
Shigernori Kenji,
Saito Masayoshi,
Sasao Mitsuo,
Harada Shoji,
Shigeta Yosuke,
Yamada Koichi,
Muraoka Hideo,
Takagi Satoshi,
Maruyarna Katsuya,
Kono Hiroaki
Publication year - 1989
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1989.tb00317.x
Subject(s) - aldehyde dehydrogenase , phenotype , ethanol , isoelectric focusing , chemistry , chromatography , biochemistry , enzyme , gene
The ethanol patch test, which is considered to be a cutaneous model of flushing, was performed on 311 healthy Japanese (237 adults and 74 children). By comparing the results with aldehyde dehydrogenase (ALDH) phenotype determined by isoelectric focusing from hair root samples, it was demonstrated that the ethanol patch test is a good indicator of the ALDH phenotype. The usefulness of this test in future studies was discussed.