Premium
Increase in Fast Hemoglobin Concentration after Incubation with Acetaldehyde Detected by an Electrophoretic Method
Author(s) -
Hawthorne G. C.,
Moms T. C. M.,
Fleming I.,
Hayes J. R.
Publication year - 1984
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1984.tb05731.x
Subject(s) - acetaldehyde , incubation , hemoglobin , chemistry , chromatography , yield (engineering) , electrophoresis , incubation period , biochemistry , ethanol , materials science , metallurgy
Incubation of acetaldehyde with hemoglobin has been shown by chromatographic methods to result in an increase in fast hemoglobin. We have studied this increase in fast hemoglobin concentration by, a gel electrophoretic method. Increases in fast hemoglobin concentration are detected following incubation with concentration8 of 100μm acetaldehyde and no further increase in yield occurs with concentrations greater than 7 mm acetaldehyde. The reaction is complete within 5 hr and the product is stable with a half‐life of greater than 12 days.