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Ethanol Clearance in Nine Inbred Rat Strains
Author(s) -
Erickson Carlton K.
Publication year - 1984
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1984.tb05710.x
Subject(s) - inbred strain , ethanol , strain (injury) , biology , medicine , endocrinology , chemistry , genetics , biochemistry , anatomy , gene
The rate of ethanol disappearance was determined for each of eight inbred rat strains and the N/Nih line of heterogeneous rats. There are significant differences in ethanol elimination rates in the strains tested. Females have rates significantly different from those of males in five of the eight inbred strains and in the N/Nih line. Castration of males alters the rate of elimination only in the F344/N strain.