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Initial Sensitivity of Rat Inbred Strains to Acute Alcohol
Author(s) -
Deitrich Richard A.,
Baker Rodney C.
Publication year - 1984
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1984.tb05709.x
Subject(s) - aldehyde dehydrogenase , ethanol , phenobarbital , alcohol , alcohol dehydrogenase , aldehyde , ethanol metabolism , inbred strain , blood alcohol , biochemistry , alcohol tolerance , endocrinology , chemistry , enzyme , medicine , biology , gene , poison control , environmental health , injury prevention , catalysis
The ethanol sensitivity of eight inbred strains and one heterogeneous stock of rats has been determined by the assessment of “sleep time” and blood alcohol levels upon awakening. In addition, levels of liver alcohol and aldehyde dehydrogenases and phenobarbital‐inducible aldehyde dehydrogenase were determined. These data are presented as baseline values for correlation and selective breeding studies using the heterogeneous rats.