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Relationship of Endocrine Status on the Stimulatory Effect of Ethanol on Hepatic Very Low Density Lipoprotein Synthesis
Author(s) -
Lakshmanan M. R.,
Felver Michael E.,
Ezekiel Mildred
Publication year - 1984
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1984.tb05680.x
Subject(s) - medicine , endocrinology , ethanol , endocrine system , stimulation , chemistry , lipoprotein , fatty acid , cholesterol , biochemistry , hormone
The normal stimulatory effect of an acute oral dose of ethanol on hepatic very low density lipoprotein synthetic rate is abolished in thyroidectomized rats but not in adrenalectomized rats. This lack of stimulation by ethanol can be explained in part by the decreased rate of hepatic fatty acid esterification to neutral lipids in thyroidectomized animals.