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Effects of Chronic Ethanol Feeding on Sympathetic Innervated Organs: Temporal Sequence of Biochemical, Functional, and Trophic Changes
Author(s) -
Rubio M. C.,
Perec C. J.,
Medina J. H.,
Tiscomia O. M.
Publication year - 1984
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1984.tb05029.x
Subject(s) - medicine , endocrinology , tyrosine hydroxylase , norepinephrine , phenylethanolamine , trophic level , biology , sympathetic nervous system , monoamine oxidase , dopamine , endogeny , enzyme , biochemistry , ecology , blood pressure
In noradrenergic nerves as well as In effector organs of the sympathetic nervous system, chronic ethanol feeding induced biochemical, functional, and trophic changes. The time sequence of modifications in the activities of tyrosine hydroxylase, phenylethanolamine‐N‐methyl transferase, monoamine oxidase, endogenous norepinephrine levels, as well as the neuronal uptake mechanism and secretory responses to norpinephrine in the submaxillary gland of the rat confirms that the effects of chronic ethanol administration are related to an increase in sympathetic tone.