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In Utero Alcohol Exposure and Developmental Delay of Response Inhibition
Author(s) -
Abel Ernest L.
Publication year - 1982
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1982.tb04993.x
Subject(s) - offspring , perseveration , in utero , spontaneous alternation , alcohol , ontogeny , pregnancy , developmental psychology , psychology , medicine , endocrinology , biology , fetus , neuroscience , cognition , biochemistry , genetics , hippocampus
Offspring of rats fed liquid alcohol diet during pregnancy exhibited age‐related Increased activity and deficits in passive avoidance learning and response perseveration which were not age‐related. Alcohol‐exposed offspring also elicited less maternal responsiveness from nontreated dams than did pair‐fed controls. The results suggest that in utero alcohol exposure produces a developmental delay in ontogeny of response inhibition mechanisms underlying activity, but not passive avoidance learning or spontaneous alternation .