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Chronic Alcohol Abuse and High Density Lipoprotein Cholesterol
Author(s) -
Barboriak Joseph J.,
Jacobson George R.,
Cushman Paul,
Herrington Roland E.,
Lipo Robert F.,
Daley Mark E.,
Anderson Alfred J.
Publication year - 1980
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1980.tb04829.x
Subject(s) - abstinence , alcohol , alcohol abuse , medicine , high density lipoprotein , cholesterol , alcohol consumption , low density lipoprotein , endocrinology , gastroenterology , biology , psychiatry , biochemistry
The possible use of high density lipoprotein cholesterol (HDLC) as a marker of alcohol abuse was studied in 92 alcoholic patients entering an inpatient treatment program. The average HDLC levels of 68 male patients (66 ± 23 mg/dl) and 24 female patients (83 ± 18 mg/dl) were significantly higher than the values for the corresponding control groups of similar ages. Approximately 20% of the male patients had HDLC levels over the mean ± 2 SD over the control groups. Following 2 wk of alcohol abstinence. the HDLC levels decreased to the control range. HDLC, as a measure of alcohol abuse, may be especially useful in combination with determination of gamma glutamyl transpeptidase (GGT), since these two tests singly or in combination were elevated in 65% of the male and 85% of the female patients.