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Mechanisms of Host Defense in Well Nourished Patients With Chronic Alcoholism
Author(s) -
Ericsson Charles D.,
Kohl Steve,
Pickering Larry K.,
Davis Jan,
Glass George S.,
Faillace Louis A.
Publication year - 1980
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1980.tb04811.x
Subject(s) - immune system , immunology , chronic alcoholism , disease , immunity , monocyte , cellular immunity , chronic disease , medicine , chronic granulomatous disease
Tests of immune function were performed on five recently abstinent, well nourished, and disease‐free patients with chronic alcoholism. No significant defects in adherence, metabolic, or bactericidal activity of polymorphonuclear leukocytes were found when compared to sex‐matched controls. Antibody‐dependent and natural killer cellular cytotoxicity of monocyte‐macrophages and lymphocytes also were normal. These data support the concept that immunity might be intact in the group of patients with chronic alcoholism who are recently sober, well nourished, and free of underlying disease.