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Enhancement of Host Susceptibility to Staphylococcus aureus Infection by Chronic Ethanol Ingestion–Modification by Glucan Immunostimulation
Author(s) -
Luzio Nicholas R. Di,
Williams David L.
Publication year - 1980
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1980.tb04810.x
Subject(s) - immunostimulant , staphylococcus aureus , ethanol , microbiology and biotechnology , glucan , ingestion , immune system , medicine , immunology , chemistry , biology , bacteria , biochemistry , genetics
The susceptibility of chronic ethanol‐treated mice to S. aureus infection was ascertained, as was the ability of the immunostimulant glucan to modify ethanol‐induced susceptibility to infection. Chronic alcohol‐treated mice showed enhanced sensitivity to S. aureus. The administration of glucan significantly prolonged survival in S. aureus infected control and chronic ethanol mice.