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Ethanol, Calcium, and Naloxone in Mice
Author(s) -
Boggan W. O.,
Meyer J. S.,
Middaugh L. D.,
Sparks D. L.
Publication year - 1979
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1979.tb05290.x
Subject(s) - (+) naloxone , calcium , ethanol , alcohol , chemistry , medicine , endocrinology , anesthesia , pharmacology , opioid , receptor , biochemistry
Alcohol has been reported to produce a significant reduction in the brain calcium content of rats, which could be blocked by administration of naloxone. Ethanol pretreatment failed to decrease brain cortex calcium and, in fact, increased the calcium content at higher doses. The effects of naloxone were also studied.