Premium
Fluidity and Lipid Composition of Mouse Biomembranes during Adaptation to Ethanol
Author(s) -
Chin Jane H.,
Goldstein Dora B.,
Parsons Linda M.
Publication year - 1979
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1979.tb04767.x
Subject(s) - composition (language) , adaptation (eye) , ethanol , chemistry , biochemistry , biology , neuroscience , art , literature
Showing that ethanol added in vitro increased the fluidity of mouse erythrocyte and synaptosomal membranes and that the same membranes Isolated from mice after chronic treatment with ethanol had increased cholesterol and were resistant to ethanol in vitro, the study suggests that the animals had adapted to the chronic presence of the drug by changing their membrane lipid composition to offset the fluidizing effects of ethanol.