Premium
Can Dopamine Beta‐Hydroxylase Levels Predict Adverse Reactions to Disulfiram?
Author(s) -
Ewing John A.,
Rouse Beatrice A.,
Mueller Robert A.,
Silver David
Publication year - 1978
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1978.tb04701.x
Subject(s) - disulfiram , medicine , dopamine beta monooxygenase , beta (programming language) , adverse effect , pharmacology , sedative , dopamine , endocrinology , computer science , programming language
Disulfiram had more pronounced sedative effects on healthy normal subjects with low levels of plasma dopamines‐β‐hydroxylase (DBH) than it did on subjects with higher levels. It is suggested that DBH levels might provide a means of predicting increased susceptibility to disulfiram side effects.