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Summary of the Discussion
Author(s) -
Lieber C. S.
Publication year - 1977
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/j.1530-0277.1977.tb05766.x
Subject(s) - ethanol , catalase , mechanism (biology) , chemistry , medicine , endocrinology , biochemistry , philosophy , enzyme , epistemology
SUMMARY There was general agreement that catalase cannot account for the activity of MEOS and that chronic ethanol feeding results in increased rates of ethanol metabolism. There was disagreement however on the mechanism of the latter effect, with some invoking the ADH pathway exclusively in association with a hypermetabolic state, whereas according to others MEOS plays a significant role in the adaptive increase of ethanol metabolism.