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Correlation between clinical/neurophysiological findings and quality of life in Charcot‐Marie‐Tooth type 1A
Author(s) -
Padua Luca,
Shy Michael E.,
Aprile Irene,
Cavallaro Tiziana,
Pareyson Davide,
Quattrone Aldo,
Rizzuto Nicolo,
Vita Giuseppe,
Tonali Pietro,
Sche Angelo
Publication year - 2008
Publication title -
journal of the peripheral nervous system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 67
eISSN - 1529-8027
pISSN - 1085-9489
DOI - 10.1111/j.1529-8027.2008.00159.x
Subject(s) - tooth disease , quality of life (healthcare) , medicine , cohort , correlation , heel , physical therapy , cohort study , physical medicine and rehabilitation , disease , nursing , anatomy , geometry , mathematics
Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot‐Marie‐Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot‐Marie‐Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.