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New antibiotic therapies for acne and rosacea
Author(s) -
MAYS RANA MAJD,
GORDON RACHEL A.,
WILSON JANICE M.,
SILAPUNT SIRUNYA
Publication year - 2012
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/j.1529-8019.2012.01497.x
Subject(s) - rosacea , acne , medicine , antibiotics , dermatology , dosing , acne treatment , intensive care medicine , pharmacology , microbiology and biotechnology , biology
Acne and rosacea compromise a substantial portion of the dermatology clinical practice. Over the past century, many treatment modalities have been introduced with antibiotics playing a major role. Today, both oral and topical antibiotics are used in the management of acne and rosacea, with several novel formulations and/or combination regimens recently introduced. The latest studies suggest anti‐inflammatory actions to be the most likely mechanism of antibiotics in acne and rosacea, shifting the focus to subantimicrobial‐dose oral antibiotics and/or topical antibiotic regimens as the preferred first‐line agents. Here we will discuss the most recent oral and topical antibiotic therapies available for treatment of acne and rosacea, with special focus on efficacy data, indication, dosing, and mechanism of action.