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Psoriatic arthritis
Author(s) -
Wollina Uwe,
Unger Leonore,
Heinig Birgit,
Kittner Thomas
Publication year - 2010
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/j.1529-8019.2010.01306.x
Subject(s) - dactylitis , medicine , psoriatic arthritis , enthesitis , psoriasis , spondylarthropathies , dermatology , disease , arthritis , nail disease , uveitis , immunology
Psoriatic arthritis (PSA) is an entity of inflammatory joint disease associated with psoriasis. PSA belongs to the heterogeneous group of seronegative spondylarthropathies. Both peripheral joints and axial skeleton can be affected in a characteristic pattern. In addition to that, enthesitis and dactylitis are important extracutaneous manifestations. Uveitis anterior is temporarily seen in about one quarter of PSA patients. There is a closer relationship of nail and joint disease. This review provides data on drug and physical treatment options. In particular DMARDS and inhibitors of tumor necrosis factor α are established therapies with importance for quality of life and long term outcome. New drugs are tested in various trials.