Premium
Health effects of vitamin D
Author(s) -
BischoffFerrari Heike
Publication year - 2010
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/j.1529-8019.2009.01288.x
Subject(s) - medicine , vitamin d and neurology , randomized controlled trial , epidemiology , disease , vitamin , cardiovascular health , health benefits , clinical trial , intensive care medicine , gerontology , traditional medicine
Increasing data suggest that many or most adults in the United States and Europe would benefit from vitamin D supplements. This review summarizes the benefits of vitamin D with the strongest evidence today from randomized controlled trials for fall and fracture prevention. Beyond fall and fracture prevention, vitamin D may also reduce overall morbidity by multiple mechanisms. Prospective epidemiological studies supported by strong mechanistic evidence suggest a reduction of cardiovascular disease (incident hypertension and cardiovascular mortality) and colorectal cancer, extending to weaker evidence on immune‐modulatory and anti‐inflammatory benefits of vitamin D.