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Cutaneous signs of neonatal and infantile immunodeficiency
Author(s) -
Mirchandani Nina,
Hawit Faris,
Silverberg Nanette B.
Publication year - 2005
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/j.1529-8019.2005.05015.x
Subject(s) - medicine , pediatrics , life expectancy , incidence (geometry) , severe combined immunodeficiency , immunodeficiency , pregnancy , human immunodeficiency virus (hiv) , quality of life (healthcare) , immunology , population , immune system , biochemistry , chemistry , physics , genetics , environmental health , nursing , biology , optics , gene
Immunodeficiencies frequently present in the skin antepartum and in the first year of life. Although genetic immunodeficiencies are uncommon, the worldwide incidence of the acquired immunodeficiency human immunodeficiency virus (HIV) is growing. Early diagnosis and treatment of neonatal immunodeficiencies and associated infections result in improved quality of life and longer life expectancy for these patients. In developed countries, improvements in therapy of HIV during pregnancy have resulted in reduced transmission to the neonate. This article reviews the common presentations and therapy of genetic and acquired neonatal immunodeficiencies.