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Febrile infection–related epilepsy syndrome (FIRES): Does duration of anesthesia affect outcome?
Author(s) -
Kramer Uri,
Chi ChingShiang,
Lin KuangLin,
Specchio Nicola,
Sahin Mustafa,
Olson Heather,
Kluger Gerhard,
van Baalen Andreas
Publication year - 2011
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2011.03230.x
Subject(s) - medicine , status epilepticus , epilepsy , coma (optics) , retrospective cohort study , affect (linguistics) , pediatrics , refractory (planetary science) , anesthesia , epilepsy syndromes , psychiatry , psychology , physics , communication , astrobiology , optics
Summary We conducted a retrospective multicenter study on children who had been included in eight studies published between November 2001 and July 2010 to explore the correlations between burst‐suppression coma (BSC) with outcome in febrile infection‐related epilepsy syndrome (FIRES). The 77 enrolled patients presented with prolonged refractory status epilepticus. BSC was induced in 46 patients. Cognitive levels at follow‐up were significantly associated with duration of a BSC (p = 0.005). The outcome of FIRES is poor. Treatment by inducing a prolonged BSC was associated with a worse cognitive outcome.