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Radiofrequency lesioning for epileptogenic periventricular nodular heterotopia: A rational approach
Author(s) -
Schmitt Friedhelm C.,
Voges Juergen,
Buentjen Lars,
Woermann Friedrich,
Pannek Heinz W.,
Skalej Martin,
Heinze HansJochen,
Ebner Alois
Publication year - 2011
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2011.03116.x
Subject(s) - heterotopia (medicine) , epilepsy , neurosurgery , medicine , neuroscience , psychology , epilepsy surgery , cortex (anatomy) , surgery , pathology
Summary Periventricular nodular heterotopias (PNHs) are frequently associated with pharmacoresistant epilepsy. They are considered part of a dysfunctional network, connected to the overlying cortex. Therefore, removal of the PNHs and additional cortectomy or lobectomy seem to be essential for significant and long‐lasting seizure reduction. These procedures, however, can have considerable limitations, especially in patients with functional eloquent cortex adjacent to the PNH. Alternatively, stereotactic neurosurgery can reduce the surgical trauma. Presented is a 56‐year‐old man who became seizure‐free after stereotactically guided radiofrequency lesioning of a solitary PNH.