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Clinical features of seizures associated with parahippocampal/inferior temporal lesions compared to those with hippocampal sclerosis
Author(s) -
Mirandola Laura,
Badawy Radwa A.,
Saunders Ann M.,
McIntosh Anne,
Berkovic Samuel F.,
Jackson Graeme D.
Publication year - 2010
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2010.02537.x
Subject(s) - hippocampal sclerosis , hippocampal formation , neuroscience , epilepsy , medicine , multiple sclerosis , clinical neurology , central nervous system disease , temporal lobe , hippocampus , psychology , pathology , psychiatry
Summary Temporal lobe epilepsy (TLE) is not a unitary electroclinical imaging syndrome. We asked if seizures arising from the parahippocampal‐inferior temporal (PIT) region differ from those associated with hippocampal sclerosis (HS). The electroclinical features of 22 patients with HS and 14 patients with lesions in the PIT region who underwent epilepsy surgery and were seizure free for at least 2 years postoperatively were analyzed retrospectively. Patients with PIT lesions had a higher frequency of hypermotor and bilateral features and a lower frequency of behavioral arrest at the onset of seizure compared to cases with HS, suggesting that TLE originating in the PIT area can mimic frontal lobe epilepsy or contralateral mesial TLE.