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Assessing ketosis: Approaches and pitfalls
Author(s) -
Carmant Lionel
Publication year - 2008
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2008.01826.x
Subject(s) - ketosis , ketogenic diet , ketone bodies , medicine , intensive care medicine , endocrinology , epilepsy , psychiatry , metabolism , diabetes mellitus
SummaryAlthough the mechanism of action of the ketogenic diet (KD) remains unknown, ketones have been used as a marker of efficacy. Acetoacetate, acetone, and beta‐hydroxybutyrate can be measured in urine, blood, and breath. The value of these measures is reviewed in this paper. Future brain measures hold promise as markers of efficacy, but research focused on the mechanisms of the KD should help to develop more reliable markers of efficacy.