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Pathways to discovery in epilepsy research: Rethinking the quest for cures
Author(s) -
Lowenstein Daniel H.
Publication year - 2008
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2007.01309.x
Subject(s) - epilepsy , multidisciplinary approach , translational research , neuroscience , translational science , scientific discovery , medicine , the internet , engineering ethics , psychology , psychiatry , computer science , cognitive science , sociology , engineering , pathology , world wide web , social science
SummaryThis paper, based on the 4th Annual Hoyer Lecture presented at the 2006 annual meeting of the American Epilepsy Society, first provides a general view of the current limitations in therapies aimed at achieving the goal of “no seizures, no side effects” for patients living with epilepsy. Some of the seminal discoveries in epilepsy research over the past 100 years are then reviewed, with an emphasis on the pivotal role of basic and clinical/translational science in leading the way to new and effective means for diagnosing and treating for epilepsy. The paper concludes with a view of the future course of epilepsy research. Scientific advances will increasingly rely on the collaboration of multidisciplinary teams of reseachers using the analytic and storage capabilities of machines, and linked together by communication tools such as the Internet and related technologies.