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A Controlled Prospective Investigation of Psychiatric Comorbidity in Temporal Lobe Epilepsy
Author(s) -
Jones Jana E.,
Bell Brian,
Fine Jason,
Rutecki Paul,
Seidenberg Michael,
Hermann Bruce
Publication year - 2007
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2007.01217.x
Subject(s) - epilepsy , temporal lobe , context (archaeology) , comorbidity , psychiatry , mood disorders , psychology , psychiatric comorbidity , mood , medicine , anxiety , paleontology , biology
Summary Temporal lobe epilepsy patients (n = 48) and healthy controls (n = 69) underwent structured psychiatric interview at baseline and 4 years later to characterize the course of DSM‐IV Axis I disorders. Adjusting for the influence of prior psychiatric history, epilepsy subjects exhibit significantly greater risk of interval episodes of Total Axis I Disorders and Mood Disorders, indicating a poorer prognosis for these comorbidities in the context of chronic temporal lobe epilepsy.