Premium
Pilot Study of Trigeminal Nerve Stimulation (TNS) for Epilepsy: A Proof‐of‐Concept Trial
Author(s) -
DeGiorgio Christopher M.,
Shewmon Alan,
Murray Diane,
Whitehurst Todd
Publication year - 2006
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1528-1167.2006.00594.x
Subject(s) - supraorbital nerve , trigeminal nerve , medicine , epilepsy , stimulation , anesthesia , infraorbital nerve , trigeminal neuralgia , reflex , corneal reflex , psychiatry
Summary: The safety and preliminary efficacy of trigeminal nerve stimulation (TNS) for epilepsy was evaluated in a pilot feasibility study of transcutaneous stimulation of the infraorbital and supraorbital branches of the trigeminal nerve. TNS was well tolerated. Four (57%) of seven subjects who completed ≥3 months experienced a ≥50% reduction in seizure frequency. The results of this pilot study support further investigation into the safety and efficacy of TNS for epilepsy.